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Principal AI Engineer – Automation & AI

April 27, 2026

eClinical Solutions is a global leader in clinical data intelligence, delivering the elluminate® Clinical Data Cloud® — an AI-powered platform driving agentic data review, SDTM automation, and RBQM for 18 of the top 50 pharmaceutical companies worldwide. As part of our eNOVA AI-First transformation, we are embedding AI across every pillar of clinical development and enterprise operations — compressing cycle times, improving data quality, and redefining how work gets done. As we scale our AI capabilities, we are building a high-impact, hands-on AI engineering function focused on delivering real, production-grade automation across the enterprise. You will make an impact: The Principal AI Engineer – Automation & AI is a hands-on technical leader responsible for designing, building, and deploying AI-powered automation solutions across eClinical Solutions. This role is builder-first (70–80% hands-on development) and operates within a small, high-output team (2–4 engineers). You will work directly with the CTAO and business leaders to identify high-value use cases and rapidly translate them into working AI systems in production. This is not a program management or oversight role. You are expected to build, ship, and iterate continuously, leveraging modern AI tooling and agentic frameworks to deliver measurable impact. Accelerate your skills and career within a fast-growing company while impacting the future of healthcare. Your day to day: Building & Shipping AI Systems <ul> <li>Design and deploy agentic AI workflows and automation solutions across enterprise functions including R&D, Engineering, Professional Services, IT, Finance, Sales, and Marketing</li> <li>Build production-grade systems such as:</li> <ul> <li>Multi-agent workflows</li> <li>RAG-based applications</li> <li>Document intelligence and summarization pipelines</li> <li>Workflow and process automation solutions</li> </ul> <li>Use modern AI tools and frameworks including:</li> <ul> <li>Codex, Claude Code, Gemini, NotebookLM</li> <li>LangChain, LangGraph, LlamaIndex (or equivalents)</li> </ul> <li>Rapidly prototype, validate, and deploy solutions in weeks, not months</li> </ul> Owning End-to-End Delivery <ul> <li>Translate business problems into working AI systems</li> <li>Design lightweight architectures and iterate quickly</li> <li>Develop and implement:</li> <ul> <li>Prompt engineering strategies</li> <li>Orchestration logic</li> <li>API integrations and data pipelines</li> <li>Testing, validation, and monitoring frameworks</li> </ul> <li>Partner directly with stakeholders to refine outputs and drive adoption</li> </ul> Driving High-Velocity Execution <ul> <li>Deliver continuous output with weekly or bi-weekly releases</li> <li>Prioritize use cases based on:</li> <ul> <li>ROI and business impact</li> <li>Technical feasibility</li> <li>Speed to value</li> </ul> <li>Operate with minimal process and high accountability in a fast-paced environment</li> </ul> Contributing to Scalable AI Foundations <ul> <li>Build and maintain reusable assets including:</li> <ul> <li>Prompt templates</li> <li>Agent design patterns</li> <li>Integration utilities</li> </ul> <li>Contribute to lightweight standards for:</li> <ul> <li>Security and data handling</li> <li>Responsible AI practices</li> <li>Evaluation and performance monitoring</li> </ul> </ul> Technical Leadership & Mentorship <ul> <li>Provide technical guidance to a small team of AI engineers and automation specialists</li> <li>Lead by example through hands-on contribution</li> <li>Support the evolution of the AI engineering function as it scales</li> </ul> Take the first step towards your dream career. Here is what we are looking for in this role. Qualifications: <ul> <li>Bachelor’s degree in Computer Science, Engineering, Data Science, or a related technical field</li> <li>6–10+ years of software engineering experience with recent hands-on work in AI/LLM systems</li> <li>Proven experience building and deploying:</li> <ul> <li>LLM-powered applications</li> <li>Agentic workflows</li> <li>Automation solutions in production environments</li> </ul> <li>Strong hands-on experience with tools such as:</li> <ul> <li>Codex, Claude Code, Gemini, NotebookLM (or similar AI-assisted development tools)</li> <li>LangChain, LangGraph, LlamaIndex, or equivalent frameworks</li> </ul> <li>Proficiency in:</li> <ul> <li>Python</li> <li>API development and system integration</li> <li>Cloud platforms (AWS, Azure, or GCP)</li> </ul> </ul> Preferred <ul> <li>Experience with:</li> <ul> <li>RAG architectures and vector databases</li> <li>AI evaluation frameworks, guardrails, and monitoring</li> <li>Workflow automation tools and enterprise integrations</li> </ul> <li>Experience working in regulated environments (e.g., life sciences, healthcare, financial services)</li> <li>Familiarity with clinical data, CDISC standards, or clinical development workflows</li> <li>Experience in high-growth or PE-backed SaaS environments</li> </ul> Accelerate your skills and career within a fast-growing company while impacting the future of healthcare. We have shared our story, now we look forward to learning yours! eClinical is a winner of the 2025 Top Workplaces USA Award for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards celebrating our exceptional company vision, values, and work-life balance. See all the details here: <a href="https://nam02.safelinks.protection.outlook.com/?url=https%3A%2F%2Ftopworkplaces.com%2Fcompany%2Feclinical-solutions%2F&data=05%7C02%7Cabrown%40eclinicalsol.com%7C4cfa7e54c4dd4513b8b708de13373e46%7Cc55122ac90d94dc2be1508d0cc3c5114%7C0%7C0%7C638969325148541920%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=idjwFyf1zAA7oHoLAFsbAWxHnw0dbwimaeHmdtvZw%2Fg%3D&reserved=0">https://topworkplaces.com/company/eclinical-solutions/</a> eClinical Solutions is a people first organization. Our inclusive culture values the contribution that diversity brings to our business. We celebrate individual experiences that connect us and that inspire innovation in our community. Our team seeks out opportunities to learn, grow and continuously improve. Bring your authentic self, you are welcome here! We are proud to be an equal opportunity employer that values diversity. Our management team is committed to the principle that employment decisions are based on qualifications, merit, culture fit and business need. <div class="content-pay-transparency"><div class="pay-input"><div class="description">Pay Range </div><div class="title">US Pay Ranges </div><div class="pay-range">$160,000—$200,000 USD</div></div></div>

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Common Interview Questions And Answers

1. HOW DO YOU PLAN YOUR DAY?

This is what this question poses: When do you focus and start working seriously? What are the hours you work optimally? Are you a night owl? A morning bird? Remote teams can be made up of people working on different shifts and around the world, so you won't necessarily be stuck in the 9-5 schedule if it's not for you...

2. HOW DO YOU USE THE DIFFERENT COMMUNICATION TOOLS IN DIFFERENT SITUATIONS?

When you're working on a remote team, there's no way to chat in the hallway between meetings or catch up on the latest project during an office carpool. Therefore, virtual communication will be absolutely essential to get your work done...

3. WHAT IS "WORKING REMOTE" REALLY FOR YOU?

Many people want to work remotely because of the flexibility it allows. You can work anywhere and at any time of the day...

4. WHAT DO YOU NEED IN YOUR PHYSICAL WORKSPACE TO SUCCEED IN YOUR WORK?

With this question, companies are looking to see what equipment they may need to provide you with and to verify how aware you are of what remote working could mean for you physically and logistically...

5. HOW DO YOU PROCESS INFORMATION?

Several years ago, I was working in a team to plan a big event. My supervisor made us all work as a team before the big day. One of our activities has been to find out how each of us processes information...

6. HOW DO YOU MANAGE THE CALENDAR AND THE PROGRAM? WHICH APPLICATIONS / SYSTEM DO YOU USE?

Or you may receive even more specific questions, such as: What's on your calendar? Do you plan blocks of time to do certain types of work? Do you have an open calendar that everyone can see?...

7. HOW DO YOU ORGANIZE FILES, LINKS, AND TABS ON YOUR COMPUTER?

Just like your schedule, how you track files and other information is very important. After all, everything is digital!...

8. HOW TO PRIORITIZE WORK?

The day I watched Marie Forleo's film separating the important from the urgent, my life changed. Not all remote jobs start fast, but most of them are...

9. HOW DO YOU PREPARE FOR A MEETING AND PREPARE A MEETING? WHAT DO YOU SEE HAPPENING DURING THE MEETING?

Just as communication is essential when working remotely, so is organization. Because you won't have those opportunities in the elevator or a casual conversation in the lunchroom, you should take advantage of the little time you have in a video or phone conference...

10. HOW DO YOU USE TECHNOLOGY ON A DAILY BASIS, IN YOUR WORK AND FOR YOUR PLEASURE?

This is a great question because it shows your comfort level with technology, which is very important for a remote worker because you will be working with technology over time...